Kals am Großglockner is a municipality in the district of Lienz in the exclave of East Tirol in the Austrian state of Tyrol. Kals is located in northern East Tirol, near the border to Salzburg and Carinthia. Located in the valleys of Kalser and Iseltals on the Kalserbach river, Kals is dominated by mountains, and the famous Großglockner mountain, the tallest mountain in all of Austria, is located partly in the municipality.